Integrative Computational Modeling of Cardiomyocyte Calcium Handling and Cardiac Arrhythmias: Current Status and Future Challenges
Cardiomyocyte calcium-handling is the key mediator of cardiac excitation-contraction coupling. In the healthy heart, calcium controls both electrical impulse propagation and myofilament cross-bridge cycling, providing synchronous and adequate contraction of cardiac muscles. However, calcium-handling...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/11/7/1090 |