Metamorphosis of Topical Semisolid Products—Understanding the Role of Rheological Properties in Drug Permeation under the “in Use” Condition

Metamorphosis of Topical Semisolid Products—Understanding the Role of Rheological Properties in Drug Permeation under the “in Use” Condition

When developing topical semisolid products, it is crucial to consider the metamorphosis of the formulation under the “in use” condition. Numerous critical quality characteristics, including rheological properties, thermodynamic activity, particle size, globule size, and the rate/extent of drug relea...

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Bibliographic Details
Main Authors: Xuping Jin, Seyed Ebrahim Alavi, Abbas Shafiee, Vania Rodrigues Leite-Silva, Kiarash Khosrotehrani, Yousuf Mohammed
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
metamorphosis
topical semisolid products
lidocaine
rheological properties
in vitro permeation studies
Online Access:https://www.mdpi.com/1999-4923/15/6/1707

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https://www.mdpi.com/1999-4923/15/6/1707

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