Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs.

Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs.

Adherence of microbes to host tissues is a hallmark of infectious disease and is often mediated by a class of adhesins termed MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Numerous pathogens express MSCRAMMs that specifically bind the heterodimeric human glycoprotein...

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Bibliographic Details
Main Authors: Xiaowen Liang, Brandon L Garcia, Livia Visai, Sabitha Prabhakaran, Nicola A G Meenan, Jennifer R Potts, Martin J Humphries, Magnus Höök
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4951027?pdf=render

Internet

http://europepmc.org/articles/PMC4951027?pdf=render

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