Transcription factors in fibroblast plasticity and CAF heterogeneity

Transcription factors in fibroblast plasticity and CAF heterogeneity

Abstract In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro-tumoral stromal microenvironment. Howeve...

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Bibliographic Details
Main Authors: Roberta Melchionna, Paola Trono, Anna Di Carlo, Francesca Di Modugno, Paola Nisticò
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cancer Associated fibroblasts (CAFs)
Transcription factors (TFs)
CAF activation
CAF subtypes
Fibrosis
Online Access:https://doi.org/10.1186/s13046-023-02934-4

Internet

https://doi.org/10.1186/s13046-023-02934-4

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