New avenues of combating antibiotic resistance by targeting cryptic pockets

Antibiotic resistance is a global health concern that is rapidly spreading among human and animal pathogens. Developing novel antibiotics is one of the most significant approaches to surmount antibiotic resistance. Given the difficult in identifying novel targets, cryptic binding sites provide new p...

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Bibliographic Details
Main Authors: Yangyang Gao, Huimin Chen, Weicheng Yang, Shuang Wang, Daohong Gong, Xiao Zhang, Yuanqin Huang, Vinit Kumar, Qiuqian Huang, W.M.W.W. Kandegama, Gefei Hao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824004407