Association of JAK/STAT genetic variants with cutaneous melanoma

Association of JAK/STAT genetic variants with cutaneous melanoma

BackgroundThe Janus-activated kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway regulates cutaneous melanoma (CM) development and progression. The JAK1, JAK2, and STAT3 proteins are encoded by polymorphic genes. This study aimed to verify whether single-nucleotid...

Full description

Bibliographic Details
Main Authors: Gabriela Vilas Bôas Gomez, Gustavo Jacob Lourenço, Lummy Maria Oliveira Monteiro, Rafael Silva Rocha, Kimberly Anne McGrail Fernández, Juan Angel Recio, Caroline Torricelli, Lilian Oliveira Coser, Alexandre Leite Rodrigues Oliveira, Juliana Carron, Aparecida Machado Moraes, Carmen Silvia Passos Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
cutaneous melanoma
JAK1
JAK2
STAT3
genetic variant
risk
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.943483/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.943483/full

Similar Items