Effect of endoplasmic reticulum stress on the osteogenic differentiation of periodontal ligament cells under continuous static pressure

Effect of endoplasmic reticulum stress on the osteogenic differentiation of periodontal ligament cells under continuous static pressure

Objective To study the effect of continuous static pressure on the endoplasmic reticulum of human periodontal ligament cells (hPDLCs) and the mechanism of osteogenic differentiation.Methods hPDLCs cultured in vitro were subjected to 1 g/cm 2 of continuous compressive pressure (CCP) by custom-made, r...

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Bibliographic Details
Main Authors: REN Qingyuan, HE Wulin, WANG Qing, CHU Hongxing, LIN Haiyan
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2019-08-01
Series:口腔疾病防治
Subjects:
human periodontal ligament cells
PERK-eIF2α-ATF4 pathway
endoplasmic reticulum stress
continuously compressive pressure
osteogenic differentiation
Online Access:http://manu45.magtech.com.cn/Jwk3_kqjbfz/EN/10.12016/j.issn.2096-1456.2019.08.002

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http://manu45.magtech.com.cn/Jwk3_kqjbfz/EN/10.12016/j.issn.2096-1456.2019.08.002

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