Chiral Recognition of Homochiral Poly (amidoamine) Dendrimers Substituted with <i>R</i>- and <i>S</i>-Glycidol by Keratinocyte (HaCaT) and Squamous Carcinoma (SCC-15) Cells In Vitro

Chiral Recognition of Homochiral Poly (amidoamine) Dendrimers Substituted with <i>R</i>- and <i>S</i>-Glycidol by Keratinocyte (HaCaT) and Squamous Carcinoma (SCC-15) Cells In Vitro

The generation 2 and 3 poly(amidoamine) dendrimers (PAMAM G2 and G3) were converted into N-(2,3-dihydroxy)propyl derivatives by the addition of enantiomerically pure <i>S</i>- and <i>R</i>-glycidol. The homochiral dendrimers bind to HaCaT and SCC-15 cell membranes with an <...

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Bibliographic Details
Main Authors: Małgorzata Malinga-Drozd, Łukasz Uram, Konrad Wróbel, Stanisław Wołowiec
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Polymers
Subjects:
homochiral dendrimer
chiral biorecognition
confocal microscopy
glycidol
polyamidoamine dendrimer
toxicity
Online Access:https://www.mdpi.com/2073-4360/13/7/1049

Internet

https://www.mdpi.com/2073-4360/13/7/1049

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