Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus

Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus

SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis. This study examined the relationships between se...

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Bibliographic Details
Main Authors: Rebecca A. Wood, Lauren Guthridge, Emma Thurmond, Carla J. Guthridge, Joseph M. Kheir, Rebecka L. Bourn, Catriona A. Wagner, Hua Chen, Wade DeJager, Susan R. Macwana, Stan Kamp, Rufei Lu, Cristina Arriens, Eliza F. Chakravarty, Aikaterini Thanou, Joan T. Merrill, Joel M. Guthridge, Judith A. James
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Systemic lupus erythematosus
Epstein-barr virus
Interferon
Antibodies
Disease activity
Online Access:http://www.sciencedirect.com/science/article/pii/S258990902100037X

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http://www.sciencedirect.com/science/article/pii/S258990902100037X

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