GsαR201C and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells

GsαR201C and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells

Abstract The Gsα/cAMP signaling pathway mediates the effect of a variety of hormones and factors that regulate the homeostasis of the post-natal skeleton. Hence, the dysregulated activity of Gsα due to gain-of-function mutations (R201C/R201H) results in severe architectural and functional derangemen...

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Main Authors: Biagio Palmisano, Rossella Labella, Samantha Donsante, Cristina Remoli, Emanuela Spica, Ilenia Coletta, Giorgia Farinacci, Michele Dello Spedale Venti, Isabella Saggio, Marta Serafini, Pamela Gehron Robey, Alessandro Corsi, Mara Riminucci
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00220-1

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https://doi.org/10.1038/s41413-022-00220-1

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