A More Robust Gut Microbiota in Calorie-Restricted Mice Is Associated with Attenuated Intestinal Injury Caused by the Chemotherapy Drug Cyclophosphamide

A More Robust Gut Microbiota in Calorie-Restricted Mice Is Associated with Attenuated Intestinal Injury Caused by the Chemotherapy Drug Cyclophosphamide

ABSTRACT Cyclophosphamide (CTX) is widely used in cancer chemotherapy, but it often induces mucositis, in which the disruption of the gut microbiota might play a pivotal role. Whether the manipulation of the gut microbiota can be used as a strategy to improve CTX-induced mucositis remains to be stud...

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Bibliographic Details
Main Authors: Tao Liu, Yanqiu Wu, Linghua Wang, Xiaoyan Pang, Liping Zhao, Huijuan Yuan, Chenhong Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
cyclophosphamide
Lactobacillus
calorie-restricted
gut microbiota
mucositis
Online Access:https://journals.asm.org/doi/10.1128/mBio.02903-18

Internet

https://journals.asm.org/doi/10.1128/mBio.02903-18

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