Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion Dogs

Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion Dogs

Patients with metastatic melanoma have a historically poor prognosis, but recent advances in treatment options, including targeted therapy and immunotherapy, have drastically improved the outcomes for some of these patients. However, not all patients respond to available treatments, and around 50% o...

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Bibliographic Details
Main Authors: Elin M. V. Forsberg, Rebecca Riise, Sara Saellström, Joakim Karlsson, Samuel Alsén, Valentina Bucher, Akseli E. Hemminki, Roger Olofsson Bagge, Lars Ny, Lisa M. Nilsson, Henrik Rönnberg, Jonas A. Nilsson
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
metastatic melanoma
uveal melanoma
patient-derived xenograft mouse model
adoptive T cell therapy
chimeric antigen receptor T cells
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/15/3/648

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https://www.mdpi.com/2072-6694/15/3/648

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