The Mycotoxin Patulin Inhibits the Mitochondrial Carnitine/Acylcarnitine Carrier (SLC25A20) by Interaction with Cys136 Implications for Human Health

The Mycotoxin Patulin Inhibits the Mitochondrial Carnitine/Acylcarnitine Carrier (SLC25A20) by Interaction with Cys136 Implications for Human Health

The effect of mycotoxin patulin (4-hydroxy-4H-furo [3,2c] pyran-2 [6H] -one) on the mitochondrial carnitine/acylcarnitine carrier (CAC, SLC25A20) was investigated. Transport function was measured as [<sup>3</sup>H]-carnitine<sub>ex</sub>/carnitine<sub>in</sub> ant...

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Bibliographic Details
Main Authors: Nicola Giangregorio, Annamaria Tonazzi, Cosima Damiana Calvano, Ciro Leonardo Pierri, Giovanna Incampo, Tommaso R. I. Cataldi, Cesare Indiveri
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria
carnitine carrier
patulin
cysteines
inhibition
Online Access:https://www.mdpi.com/1422-0067/24/3/2228

Internet

https://www.mdpi.com/1422-0067/24/3/2228

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