Growth/differentiation factor 15 (GDF15) expression in the heart after myocardial infarction and cardioprotective effect of pre-ischemic rGDF15 administration

Growth/differentiation factor 15 (GDF15) expression in the heart after myocardial infarction and cardioprotective effect of pre-ischemic rGDF15 administration

Abstract Growth/differentiation factor-15 (GDF15) is considered an unfavourable prognostic biomarker for cardiovascular disease in clinical data, while experimental studies suggest it has cardioprotective potential. This study focuses on the direct cardiac effects of GDF15 during ischemia–reperfusio...

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Bibliographic Details
Main Authors: Geoffrey Dogon, Eve Rigal, Eliot Potel, Marie Josse, Luc Rochette, Yannick Bejot, Catherine Vergely
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Subjects:
GDF-15
Ischemia–reperfusion injury
Heart
Preconditioning
Cardioprotection
Online Access:https://doi.org/10.1038/s41598-024-63880-5

Internet

https://doi.org/10.1038/s41598-024-63880-5

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