Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation

Fat-associated lymphoid clusters (FALC) in the serous cavities house rapid IgM-producing B1 cells, but how the clusters are activated to respond to infection is unclear. Here the authors show that in response to lung inflammation or pleural nematode infection adipose stromal cell-derived IL-33 activ...

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Bibliographic Details
Main Authors: Lucy H. Jackson-Jones, Sheelagh M. Duncan, Marlène S. Magalhaes, Sharon M. Campbell, Rick M. Maizels, Henry J. McSorley, Judith E. Allen, Cécile Bénézech
Format: Article
Language:English
Published: Nature Portfolio 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12651