Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress

Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress

<p>Abstract</p> <p>Background</p> <p>The expression of pro-angiogenic cytokines, such as vascular endothelial growth factor (VEGF) and interleukin-8/CXCL8 (IL-8), plays an important role in tumor growth and metastasis. Low oxygen tension within poorly-vascularized tumor...

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Bibliographic Details
Main Authors: Abcouwer Steve F, Bobrovnikova-Marjon Ekaterina V, Marjon Philip L
Format: Article
Language:English
Published: BMC 2004-01-01
Series:Molecular Cancer
Subjects:
Angiogenesis
glucose
glutamine
breast cancer
glucose-regulated protein 78 (GRP78)
growth arrest and DNA damage inducible gene 153 (GADD153)
tunicamycin
brefeldin A
thapsigargin
ionomycin
hypoxia
Online Access:http://www.molecular-cancer.com/content/3/1/4

Internet

http://www.molecular-cancer.com/content/3/1/4

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