Hepatic GRK2 is dispensable for glucose homeostasis and other key metabolic parameters in mice

Hepatic GRK2 is dispensable for glucose homeostasis and other key metabolic parameters in mice

Objective: G-protein-coupled receptor (GPCR) kinases (GRKs) abrogate GPCR signaling by promoting receptor desensitization and internalization. Accumulating evidence suggests that GRK2 represents an important regulator of GPCR-mediated effects on systemic glucose metabolism, obesity, and insulin resi...

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Bibliographic Details
Main Authors: Antwi-Boasiako Oteng, Srinivas Pittala, Andrea Kliewer, Yishu Qiu, Jürgen Wess
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Molecular Metabolism
Subjects:
G protein-coupled receptor
Liver
Glucose tolerance
Knockout mice
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823002004

Internet

http://www.sciencedirect.com/science/article/pii/S2212877823002004

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