Phenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans Cells.

Phenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans Cells.

Cutaneous antigen presenting cells (APCs) are critical for the induction and regulation of skin immune responses. The human skin contains phenotypically and functionally distinct APCs subsets that are present at two separated locations. While CD1ahigh LCs form a dense network in the epidermis, the C...

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Bibliographic Details
Main Authors: Cynthia M Fehres, Sven C M Bruijns, Brigit N Sotthewes, Hakan Kalay, Lana Schaffer, Steven R Head, Tanja D de Gruijl, Juan J Garcia-Vallejo, Yvette van Kooyk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4659545?pdf=render

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http://europepmc.org/articles/PMC4659545?pdf=render

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