Recruitment of Transcription Complexes to Enhancers and the Role of Enhancer Transcription

Enhancer elements regulate the tissue- and developmental-stage-specific expression of genes. Recent estimates suggest that there are more than 50,000 enhancers in mammalian cells. At least a subset of enhancers has been shown to recruit RNA polymerase II transcription complexes and to generate enhan...

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Bibliographic Details
Main Authors: Jörg Bungert, Fred Varn, John Strouboulis, Suming Huang, Jared S. Stees
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Biology
Subjects:
Online Access:http://www.mdpi.com/2079-7737/1/3/778