Welfare Assessment, End-Point Refinement and the Effects of Non-Aversive Handling in C57BL/6 Mice with Lewis Lung Cancer

Cancer-bearing mice are at risk of developing anxiety, pain, or malaise. These conditions may not only harm welfare but could also undermine data quality and translational validity in studies to develop therapeutic interventions. We aimed to establish whether, or at what point mice developing lung c...

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Bibliographic Details
Main Authors: Amy L. Miller, Johnny V. Roughan
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/12/1/23