USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity

ETS2 is a member of the ETS family of transcription factors and has been implicated in the regulation of cell proliferation, differentiation, apoptosis, and tumorigenesis. The aberrant activation of ETS2 is associated with various human cancers, highlighting its importance as a therapeutic target. U...

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Bibliographic Details
Main Authors: Yunsik Choi, Yuri Lee, Jin Seo Kim, Peijing Zhang, Jongchan Kim
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/10/1475