Disregarded determinant role of transfection medium in chitosan mediated siRNA delivery

It is well known that the chitosan (CS) properties such as molecular weight (Mw) and deacetylation degree (DD) are crucial for siRNA delivery. In the present study, we have unintentionally found that the transfection medium has much more substantial effect, which has not been reported before. Specif...

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Bibliographic Details
Main Authors: Wen Song, Qingyuan Ye, Zhe Li, Yajie Hou, Lina Niu, Zhiwei Ma, Chuanxu Yang
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127522003707