LncRNA ARGI Contributes to Virus‐Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN‐Stimulated Genes

LncRNA ARGI Contributes to Virus‐Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN‐Stimulated Genes

Abstract Type 1 diabetes (T1D) is a complex autoimmune disease that develops in genetically susceptible individuals. Most T1D‐associated single nucleotide polymorphisms (SNPs) are located in non‐coding regions of the human genome. Interestingly, SNPs in long non‐coding RNAs (lncRNAs) may result in t...

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Bibliographic Details
Main Authors: Itziar González‐Moro, Koldo Garcia‐Etxebarria, Luis Manuel Mendoza, Nora Fernández‐Jiménez, Jon Mentxaka, Ane Olazagoitia‐Garmendia, María Nicol Arroyo, Toshiaki Sawatani, Cristina Moreno‐Castro, Chiara Vinci, Anne Op de Beek, Miriam Cnop, Mariana Igoillo‐Esteve, Izortze Santin
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Advanced Science
Subjects:
long non‐coding RNAs
pancreatic β cells
single nucleotide polymorphism
type 1 diabetes
viral infections
Online Access:https://doi.org/10.1002/advs.202300063

Internet

https://doi.org/10.1002/advs.202300063

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