The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles

The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles

The N-terminus of the hepatitis B virus (HBV) large surface protein (LHB) differs with respect to genotypes. Compared to the amino terminus of genotype (Gt)D, in GtA, GtB and GtC, an additional identical 11 amino acids (aa) are found, while GtE and GtG share another similar 10 aa. Variants of GtB an...

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Bibliographic Details
Main Authors: Bingfu Jiang, Xingjian Wen, Qingyan Wu, Daniela Bender, Gert Carra, Michael Basic, Alica Kubesch, Kai-Henrik Peiffer, Klaus Boller, Eberhard Hildt
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
HBV surface protein
PreS1 deletion
HBV filaments
HBV genotypes
morphogenesis
Online Access:https://www.mdpi.com/2073-4409/9/8/1898

Internet

https://www.mdpi.com/2073-4409/9/8/1898

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