Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition

Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition

Abstract Chebulinic acid (CA), originally isolated from the flower extract of the plant Terminalia chebula, has been shown to inhibit infection of herpes simplex virus-2 (HSV-2), suggestively by inhibiting the host entry step of viral infection. Like HSV-2, the dengue virus (DENV) and chikungunya vi...

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Bibliographic Details
Main Authors: Naiju Thomas, Poonam Patil, Anjana Sharma, Sandeep Kumar, Vikas Kumar Singh, Kalichamy Alagarasu, Deepti Parashar, Suman Tapryal
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13923-6

Internet

https://doi.org/10.1038/s41598-022-13923-6

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