Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases

Mutations in the <i>LMNA</i> gene cause a collection of diseases known as laminopathies, including muscular dystrophies, lipodystrophies, and early-onset aging syndromes. The <i>LMNA</i> gene encodes A-type lamins, lamins A/C, intermediate filaments that form a meshwork under...

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Bibliographic Details
Main Authors: Sydney G. Walker, Christopher J. Langland, Jill Viles, Laura A. Hecker, Lori L. Wallrath
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/8/1142