Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis
Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes febrile chikungunya fever (CHIKF) in humans. This disease is debilitating and characterized by acute fever onset and chronic incapacitating polyarthralgia. CHIKF pathogenesis remains poorly defined with no approved vaccines and t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-08-01
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Series: | Medical Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3271/3/3/64 |