Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation

Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation

Abstract Background Influenza A viruses cause epidemics/severe pandemics that pose a great global health threat. Among eight viral RNA segments, the multiple functions of nucleoprotein (NP) play important roles in viral replication and transcription. Methods To understand how NP contributes to the v...

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Bibliographic Details
Main Authors: Su-Jhen Hung, Yin-Mei Hsu, Sheng-Wen Huang, Huey-Pin Tsai, Leo Yi Yang Lee, Aeron C. Hurt, Ian G. Barr, Shin-Ru Shih, Jen-Ren Wang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Influenza virus
Nucleoprotein
Evolution
H3N2
Ferret study
Viral replication
Online Access:https://doi.org/10.1186/s12929-019-0612-z

Internet

https://doi.org/10.1186/s12929-019-0612-z

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