Neuroanatomical Abnormalities in Behaviorally Characterized APPV717F Transgenic Mice

Histological analyses were performed on the brains of APPV717F transgenic (Tg)mice previously studied in a battery of behavioral tests. We describe here the regional and age-dependent deposition of amyloid in both heterozygous and homozygous Tg mice. We also report that Tg mice show significant and...

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Bibliographic Details
Main Authors: Jean-Cosme Dodart, Chantal Mathis, Josep Saura, Kelly R. Bales, Steven M. Paul, Arielle Ungerer
Format: Article
Language:English
Published: Elsevier 2000-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902784