High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1–AMPK–ACC Pathway

High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1–AMPK–ACC Pathway

Background: Nicotinamide mononucleotide (NMN) is the physiological circulating NAD precursor thought to elevate the cellular level of NAD<sup>+</sup> and to ameliorate various age-related diseases. An inseparable link exists between aging and tumorigenesis, especially involving aberrant...

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Bibliographic Details
Main Authors: Mingjiong Zhang, Jiahua Cui, Haoyan Chen, Yu Wang, Xingwang Kuai, Sibo Sun, Qi Tang, Feng Zong, Qiaoyu Chen, Jianqing Wu, Shuangshuang Wu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
NMN
NAM
NAMPT
ferroptosis
lung adenocarcinoma
Online Access:https://www.mdpi.com/2072-6694/15/9/2427

Internet

https://www.mdpi.com/2072-6694/15/9/2427

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