Integration of single-cell and bulk RNA sequencing to establish a prognostic signature based on tumor-associated macrophages in colorectal cancer

Integration of single-cell and bulk RNA sequencing to establish a prognostic signature based on tumor-associated macrophages in colorectal cancer

Abstract Several studies have shown significant involvement of tumor-associated macrophages (TAMs) in the tumor microenvironment and cancer progression. However, no data on reliable TAM-related biomarkers are available for predicting the prognosis of patients with colorectal cancer (CRC). We analyze...

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Bibliographic Details
Main Authors: Hua Li, Lujuan Pan, Junyu Guo, JianLe Lao, Mingwei Wei, Fuda Huang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Gastroenterology
Subjects:
Tumor-associated macrophage
Prognostic signature
Immunotherapy
Tumor microenvironment
Colorectal cancer
Online Access:https://doi.org/10.1186/s12876-023-03035-4

Internet

https://doi.org/10.1186/s12876-023-03035-4

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