Synthesis of Novel, Dual-Targeting <sup>68</sup>Ga-NODAGA-LacN-E[c(RGDfK)]<sub>2</sub> Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α<sub>v</sub>β<sub>3</sub> integrin. This receptor is overexpressed in tumor and tumor endothel...

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Bibliographic Details
Main Authors: Barbara Gyuricza, Judit P. Szabó, Viktória Arató, Dániel Szücs, Adrienn Vágner, Dezső Szikra, Anikó Fekete
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/6/796