Synthesis of Novel, Dual-Targeting <sup>68</sup>Ga-NODAGA-LacN-E[c(RGDfK)]<sub>2</sub> Glycopeptide as a PET Imaging Agent for Cancer Diagnosis
Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α<sub>v</sub>β<sub>3</sub> integrin. This receptor is overexpressed in tumor and tumor endothel...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/6/796 |