Differential effect of growth factors on invasion and proliferation of endocrine resistant breast cancer cells.

We have established several breast cancer cell lines that exhibit a permanent ER-depleted phenotype, induced by shRNA transfection of MCF-7 cells, which afford a useful model for studying acquired endocrine resistance. Previously we showed that MDA-231 as well as ER-silenced cells could invade throu...

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Bibliographic Details
Main Authors: Maitham A Khajah, Sanaa Al Saleh, Princy M Mathew, Yunus A Luqmani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408495?pdf=render