Tunneling nanotubes, TNT, communicate glioblastoma with surrounding non-tumor astrocytes to adapt them to hypoxic and metabolic tumor conditions

Abstract Cell-to-cell communication is essential for the development and proper function of multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) proliferate in several pathological conditions such as HIV, cancer, and neurodegenerative diseases. However, the nature, functi...

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Bibliographic Details
Main Authors: Silvana Valdebenito, Shaily Malik, Ross Luu, Olivier Loudig, Megan Mitchell, George Okafo, Krishna Bhat, Brendan Prideaux, Eliseo A. Eugenin
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93775-8