KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing

KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing

Abstract Background Adipose-derived stem cells (ADSCs) have been shown to accelerate diabetic wound healing by promoting neovascularization, though the underlying mechanisms are not fully understood. This study aims to explore whether ADSCs influence endothelial progenitor cells (EPCs) function to e...

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Bibliographic Details
Main Authors: Yunjia Xie, Xuejun Ni, Xiaofen Wan, Nating Xu, Lu Chen, Chensheng Lin, Xi Zheng, Beichen Cai, Qian Lin, Ruonan Ke, Tao Huang, Xuefeng Hu, Biao Wang, Xiuying Shan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cellular & Molecular Biology Letters
Subjects:
Adipose-derived stem cells
Endothelial progenitor cells
Diabetic wound
Neovascularization
Wound healing
Online Access:https://doi.org/10.1186/s11658-025-00702-0

Internet

https://doi.org/10.1186/s11658-025-00702-0

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