All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells.

All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells.

<h4>Introduction</h4>Despite recent advances in perinatal medicine, bronchopulmonary dysplasia (BPD) remains the most common complication of preterm birth. Inflammation, the main cause for BPD, results in arrested alveolarization. All trans-retinoic acid (ATRA), the active metabolite of...

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Bibliographic Details
Main Authors: Nikolaos Tsotakos, Imtiaz Ahmed, Todd M Umstead, Yuka Imamura, Eric Yau, Patricia Silveyra, Zissis C Chroneos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0272769

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https://doi.org/10.1371/journal.pone.0272769

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