Membrane Internalization Mechanisms and Design Strategies of Arginine-Rich Cell-Penetrating Peptides

Membrane Internalization Mechanisms and Design Strategies of Arginine-Rich Cell-Penetrating Peptides

Cell-penetrating peptides (CPPs) have been discovered to deliver chemical drugs, nucleic acids, and macromolecules to permeate cell membranes, creating a novel route for exogenous substances to enter cells. Up until now, various sequence structures and fundamental action mechanisms of CPPs have been...

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Bibliographic Details
Main Authors: Minglu Hao, Lei Zhang, Pu Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
CPPs
arginine-rich peptide
non-covalent interaction
mechanism of internalization
peptide design
biomedical applications
Online Access:https://www.mdpi.com/1422-0067/23/16/9038

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https://www.mdpi.com/1422-0067/23/16/9038

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