Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling

Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling

Jiang, Guo, Hao et al. investigate the role of the tumour microenvironment in breast cancer stem cell regulation and identify an arteriolar niche in which BCSCs tended to be enriched in human estrogen receptor positive breast cancer. Here, BCSCs are found to interact with arteriolar endothelial cell...

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Bibliographic Details
Main Authors: Yinan Jiang, Yichen Guo, Jinjin Hao, Rachael Guenter, Justin Lathia, Adam W. Beck, Reagan Hattaway, Douglas Hurst, Qiming Jane Wang, Yehe Liu, Qi Cao, Helen Krontiras, Herbert Chen, Roy Silverstein, Bin Ren
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02308-6

Internet

https://doi.org/10.1038/s42003-021-02308-6

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