T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea.

Obstructive sleep apnea (OSA) is a low-grade inflammatory disease affecting the cardiovascular and metabolic systems. Increasing OSA severity reduces T-regulatory lymphocytes (Tregs) in OSA children. Since Tregs modulate endothelial activation, and attenuate insulin resistance, we hypothesized that...

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Bibliographic Details
Main Authors: Hui-Leng Tan, David Gozal, Arash Samiei, Rakesh Bhattacharjee, Yang Wang, Helena Molero Ramirez, Hari P R Bandla, Richa Kulkarni, Leila Kheirandish-Gozal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728363?pdf=render