Stalled oligodendrocyte differentiation in IDH-mutant gliomas

Stalled oligodendrocyte differentiation in IDH-mutant gliomas

Abstract Background Roughly 50% of adult gliomas harbor isocitrate dehydrogenase (IDH) mutations. According to the 2021 WHO classification guideline, these gliomas are diagnosed as astrocytomas, harboring no 1p19q co-deletion, or oligodendrogliomas, harboring 1p19q co-deletion. Recent studies report...

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Main Authors: Yanfei Wei, Guanzhang Li, Jing Feng, Fan Wu, Zheng Zhao, Zhaoshi Bao, Wei Zhang, Xiaodong Su, Jiuyi Li, Xueling Qi, Zejun Duan, Yunqiu Zhang, Sandra Ferreyra Vega, Asgeir Store Jakola, Yingyu Sun, Helena Carén, Tao Jiang, Xiaolong Fan
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-023-01175-6

Internet

https://doi.org/10.1186/s13073-023-01175-6

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