Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

Abstract There is an urgent need to validate new drug targets and identify small molecules that possess activity against both drug-resistant and drug-sensitive bacteria. The enzymes belonging to amino acid biosynthesis have been shown to be essential for growth in vitro, in vivo and have not been ex...

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Bibliographic Details
Main Authors: Deepika Chaudhary, Avantika Singh, Mardiana Marzuki, Abhirupa Ghosh, Saqib Kidwai, Tannu Priya Gosain, Kiran Chawla, Sonu Kumar Gupta, Nisheeth Agarwal, Sudipto Saha, Yashwant Kumar, Krishan Gopal Thakur, Amit Singhal, Ramandeep Singh
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16468-w

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https://doi.org/10.1038/s41598-022-16468-w

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