T lymphocyte myosin IIA is required for maturation of the immunological synapse

T lymphocyte myosin IIA is required for maturation of the immunological synapse

The role of non-muscle myosin IIA (heavy chain encoded by the non-muscle myosin heavy chain 9 gene, Myh9) in immunological synapse formation is controversial. We have addressed the role of myosin IIA heavy chain protein (MYH9) in mouse T cells responding to MHC-peptide complexes and ICAM-1 in suppo...

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Bibliographic Details
Main Authors: Sudha eKumari, Santosha eVardhana, Michael eCammer, Silvia eCurado, Luis eSantos, Michael P Sheetz, Michael L. Dustin
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Calcium
Cytoskeleton
Phosphorylation
receptors
signaling
synapse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00230/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00230/full

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