Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1

ABSTRACT There is a growing interest in the use of probiotic bacteria as biosensors for the detection of disease. However, there is a lack of bacterial receptors developed for specific disease biomarkers. Here, we have investigated the use of the peptide-regulated transcription factor ComR from Stre...

Full description

Bibliographic Details
Main Authors: Michael Brasino, Eli Wagnell, E. Sila Ozdemir, Srivathsan Ranganathan, Justin Merritt
Format: Article
Language:English
Published: American Society for Microbiology 2024-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00517-24