A super TLR agonist to improve efficacy of dendritic cell vaccine in induction of anti-HCV immunity.

Persistent infections caused by pathogens such as hepatitis C virus are major human diseases with limited or suboptimal prophylactic and therapeutic options. Given the critical role of dendritic cell (DC) in inducing immune responses, DC vaccination is an attractive means to prevent and control the...

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Bibliographic Details
Main Authors: Bangxing Hong, Sung-Hyung Lee, Xiao-Tong Song, Lindsey Jones, Keigo Machida, Xue F Huang, Si-Yi Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492467?pdf=render