Phenylalanine ammonia-lyase through evolution: A bioinformatic approach

Phenylalanine ammonia-lyase (PAL) is the first entry enzyme of the phenylpropanoid pathway that converts phenylalanine to cinnamic acid which is the precursor of various secondary metabolites. PAL is recently formulated for Phenylketonuric patients in pegylated forms. Screening a PAL with the highes...

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Bibliographic Details
Main Author: Shiva Hemmati
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-03-01
Series:Trends in Pharmaceutical Sciences
Online Access:http://tips.sums.ac.ir/article_42146_3e51850eb0f3e9419374cce5b4a1c496.pdf