Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration

Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration

Asthma heterogeneity complicates the search for targeted treatment against airway inflammation and remodeling. We sought to investigate relations between eosinophilic inflammation, a phenotypic feature frequent in severe asthma, bronchial epithelial transcriptome, and functional and structural measu...

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Main Authors: Pawel Kozlik-Siwiec, Sylwia Buregwa-Czuma, Izabela Zawlik, Sylwia Dziedzina, Aleksander Myszka, Joanna Zuk-Kuwik, Andzelika Siwiec-Kozlik, Jacek Zarychta, Krzysztof Okon, Lech Zareba, Jerzy Soja, Bogdan Jakiela, Michał Kepski, Jan G. Bazan, Stanislawa Bazan-Socha
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
asthma
eosinophilic
epithelial
bronchial
airway remodeling
differential expression
Online Access:https://www.mdpi.com/1422-0067/24/4/3789

Internet

https://www.mdpi.com/1422-0067/24/4/3789

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