Puerarin Exerts Protective Effects on Wear Particle-Induced Inflammatory Osteolysis

Puerarin Exerts Protective Effects on Wear Particle-Induced Inflammatory Osteolysis

Wear particle-stimulated inflammatory bone destruction and the consequent aseptic loosening remain major postoperative problems for artificial joints. Studies have indicated that puerarin promotes osteogenesis and alleviates lipopolysaccharide-induced osteoclastogenesis in vitro. However, the underl...

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Bibliographic Details
Main Authors: Chao Yang, Juehong Li, Kechao Zhu, Xiangwei Yuan, Tao Cheng, Yebin Qian, Xianlong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
titanium particles
osteolysis
puerarin
osteoclastogenesis
ERK pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01113/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01113/full

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