An immunomodulating peptide with potential to suppress tumour growth and autoimmunity

An immunomodulating peptide with potential to suppress tumour growth and autoimmunity

Abstract Cancers and autoimmune diseases commonly co-exist and immune checkpoint inhibitor therapy (ICI) exacerbates autoimmune pathologies. We recently described a lipidic peptide, designated IK14004, that promotes expansion of immunosuppressive T regulatory (Treg) cells and uncouples interleukin-2...

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Bibliographic Details
Main Authors: Michael Agrez, Christopher Chandler, Kristofer J. Thurecht, Nicholas L. Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Benjamin Blyth, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew M. Hall, Hayley Gooding, Laura Gallagher
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47229-y

Internet

https://doi.org/10.1038/s41598-023-47229-y

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