Anti-aquaporin-1 autoantibodies in patients with neuromyelitis optica spectrum disorders.

Autoantibodies against aquaporin-4 (AQP4), a water channel in CNS astrocytes, are detected in ∼50-80% of patients with neuromyelitis optica spectrum disorders (NMOsd), characterized by longitudinally extensive transverse myelitis (LETM) and/or optic neuritis. Although these autoantibodies present an...

Full description

Bibliographic Details
Main Authors: John S Tzartos, Christos Stergiou, Konstantinos Kilidireas, Paraskevi Zisimopoulou, Thomas Thomaidis, Socrates J Tzartos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781161?pdf=render