A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination

Abstract The adaptive regulation of fear memories is a crucial neural function that prevents inappropriate fear expression. Fear memories can be acquired through contextual fear conditioning (CFC) which relies on the hippocampus. The thalamic nucleus reuniens (NR) is necessary to extinguish contextu...

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Bibliographic Details
Main Authors: Heather C. Ratigan, Seetha Krishnan, Shai Smith, Mark E. J. Sheffield
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42429-6